Guo Yu, a famous acupuncturist of the Eastern Han Dynasty served the government as an assistant minister of the Imperial Administration of Health.

One day Emperor He asked Guo: "Why could one needle cure a poor but not a noble?" Guo answered: "Nobles are usually powerful and arrogant. When seeing them, acupuncturists feel so nervous and cautious for fear of making mistakes in treatment. This, of course, definitely affects his decision. There are four difficulties in treating the nobles:

Noble patients have no confidence on physicians.